DESCRIPTION OF THE PRIMARY STRUCTURE POLYMORPHISM OF AVR4 GENE IN PHYTOPHTHORA INFESTANS (MONT.) DE BARY
Abstract
The paper describes the primary structure polymorphism of the oomycete virulence gene Avr4 in field samples of P. infestans from the Moscow and Vladimir regions of Russia. It is found that in nucleotide sequences the Avr4 gene exhibits four site of single nucleotide polymorphism that can be attributed to hot spots of mutagenesis (at 180, 278, 376 and 439). Depending on the nucleotide composition, among the non-functional variants of the Avr4 gene, five allelic variants are identified. Based on these data, it was concluded that the Avr4 gene has considerable polymorphism of the primary structure, but in order to elucidate the causes of this polymorphism and the nature of the evolution of this gene, as well as to establish the allele frequencies in populations of P. infestans, additional population-genetic studies are required.
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