CALIBRATION OF THE INHALER FOR THE PRODUCTION OF SUBMICROSCOPIC FRACTION

Abstract

The method for increasing the dispersion of
aerosol particles was developed to enhance the therapeutic
effect of drugs by inhalation them. It is shown that the use
of the sparger in a standard inhaler has increased the
proportion of submicroscopic particles (d ≤ 1 m) from 7 to
about 50%, which can substantially increase the treatment
effi ciency, improve its safety and signifi cantly reduce the
effective doses of drugs.