geomgouГеографическая среда и живые системыGeographical Environment and Living Systems2712-76132712-7621Московский государственный областной университетgeomgou-739Research ArticleСтатьиСодержание ловастатина в различных штаммах aspergillus terreusContents lovastatin in different strains aspergillus terreusГулямоваТашхан Гафуровнаimbanruz@mail.ruРузиеваДиларам Муталибовнаimb-anruz@mail.ruНасметоваСаодат Мамажановнаimb-anruz@mail.ruКаримоваФеруза Абдусаттаровнаimb-anruz@mail.ruРасуловаГульчехра Абраровнаimb-anruz@mail.ruЛобановаКсения Валентиновнаimb-anruz@mail.ruМурадовПанах Зулфигарmpanah@mail.ruИнститут микробиологии АН УзбекистанаRussian FederationИнститут микробиологии НАН АзербайджанаRussian Federation201127052022021621Copyright © Гулямова Т.Г., Рузиева Д.М., Насметова С.М., Каримова Ф.А., Расулова Г.А., Лобанова К.В., Мурадов П.З., 20222022Гулямова Т.Г., Рузиева Д.М., Насметова С.М., Каримова Ф.А., Расулова Г.А., Лобанова К.В., Мурадов П.З.Гулямова Т.Г., Рузиева Д.М., Насметова С.М., Каримова Ф.А., Расулова Г.А., Лобанова К.В., Мурадов П.З.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.geoecosreda.ru/jour/article/view/739

Изучены 30 штаммов мицелиальных грибов Aspergillus terreus, выделенных из различных почвенных образцов (ил, красная почва, корка соли с почвой), взятых из территории Республики Узбе- кистан, как возможных продуцентов ловастатина и родственных ему соединений. Выявлено 4 активных штамма исследованного вида, один из которых наряду с ловастатином способен продуцировать также незна- чительное количество симвастатина. Исходное содер- жание (до 121 мг/л) ловастатина в биомассе активных штаммов дает основание считать их вполне перспек- тивными для использования с этой целью.

30 strains of filamentous fungi Aspergillus terreus, isolated from different soil samples (red soil, the peel of salt with soil ) in Uzbekistan, as potential producers of lovastatin and related compounds have been studied. Four active strains of investigated sample have been found. One of them together with lovastatin is capable to produce small amounts of simvastatin. Original content of lovastatin in the biomass of active strains gives grounds to consider them quite promising for this purpose

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The authors declare that there are no conflicts of interest present.